The morning-after for bacterial STIs.
A single prescribed antibiotic dose taken within 72 hours after sex, to lower the chance of syphilis, chlamydia and gonorrhoea.
DoxyPEP, explained.
DoxyPEP (antibiotic post-exposure prophylaxis) means taking a single prescribed antibiotic dose once, ideally within 24 hours and no later than 72 hours after condomless sex. No more than one dose in 24 hours.
Who it’s for
- Gay, bisexual and other men who have sex with men, and transgender women, with a bacterial STI in the last 12 months (CDC 2024 guidance)
- Others your clinician judges may benefit after a full review
What’s included
- Clinician visit and prescription if appropriate
- STI testing every 3–6 months
- Guidance on timing and dosing
- Refills when you need them
DoxyPEP trial (NEJM, 2023): about a two-thirds reduction in syphilis, chlamydia and gonorrhoea among men who have sex with men and transgender women.
Published guidance or trial data — not Previe patient outcomes.
DoxyPEP, one dose
Taken as a single dose after sex. Your clinician confirms whether DoxyPEP is right for you.
Shown for illustration. Prescription only, dispensed by a licensed pharmacy after a clinician prescribes.
The antibiotic used for DoxyPEP is not used in pregnancy. It can cause sun sensitivity and stomach upset — take it with water and stay upright for 30 minutes. DoxyPEP does not prevent HIV or mpox, and it is not a substitute for regular testing.
A Previe clinician decides whether treatment is appropriate after reviewing your full history. If you are having a medical emergency, call 911.
DoxyPEP questions
Can I take it with PrEP?
Yes, many people use both. Your clinician reviews them together.
Does it work for women?
CDC guidance currently covers men who have sex with men and transgender women; evidence in cisgender women is still limited, so your clinician will discuss your options honestly.
Ready when you are.
A few questions, then join the waitlist for DoxyPEP in your state.
Check eligibility